A Breakthrough in Osteoporosis Solutions

The prestigious medical journal Nutrition Reviews has identified osteoporosis as an inflammatory disease—a fact that many doctors are still unaware of. Osteoporosis is one of the most common conditions affecting older adults. In the United States, one in every two women and one in every four men suffers from this condition, which is characterized by low bone mass and increased bone fragility, putting individuals at high risk for fractures.

Publication Date: 06/10/2022
Last Updated: 09/08/2024
Reading Time: 4 minutes

Osteoporosis is a widespread condition among older adults, leading to weakened bones and an increased risk of fractures. In the United States, the statistics are staggering: one in every two women and one in every four men are affected. Older adults with this condition often face repeated fractures that disrupt their daily lives, and in some cases, these fractures can be fatal. According to reports, about 30% of patients in the U.S. die within the first year of diagnosis. Recovery from fractures can take months, and in some cases, the damage is irreversible.

Recent Research on Osteoporosis

Recent studies have shifted the understanding of osteoporosis from a condition primarily associated with metabolic, mechanical, and endocrine factors to one driven by inflammation. The disease is part of the aging process and should be addressed accordingly when considering solutions. Researchers now recognize that osteoporosis is a result of chronic inflammation—a process that begins much earlier in life but becomes more apparent as we age.

For women, this process typically starts around the age of 45, coinciding with menopause, while in men, it begins around the age of 55. During these years, there is a significant decrease in bone mass.

Bone Density Loss as an Inflammatory Process

The latest research highlights that bone density loss is an inflammatory process. A study conducted at the Pedro Ernesto University Hospital in Rio de Janeiro concluded that inflammation is a key factor in bone degradation. Clinical and molecular evidence shows that inflammation significantly affects bone turnover. Therefore, any approach to addressing osteoporosis must consider this inflammatory component before making a diagnosis or prescribing a solution.

In an article published in Nutrition Reviews (Volume 65, Issue suppl_3, December 2007), the author connects the disease process to inflammation accompanied by cytokine secretion. A significant cause of osteoporosis is estrogen deficiency following menopause in women. However, estrogen deficiency is not the root cause but rather a consequence of the inflammatory process and cytokine release. Therefore, addressing the inflammation is crucial when dealing with osteoporosis.

A Revolutionary Approach to Osteoporosis

Amorphical, the only company in the world to approach osteoporosis as an inflammatory process, has developed a groundbreaking solution based on amorphous calcium carbonate (ACC). ACC is absorbed more effectively by the body and aids in reducing inflammation. Unlike conventional crystalline calcium supplements, Amorphical’s nano-amorphous calcium carbonate offers significantly higher absorption rates.

During absorption, ACC transforms into bicarbonate, which naturally balances the acidic environment associated with inflammation. Bicarbonate is the substance the body produces in response to inflammation, helping to balance the body’s natural acidity. Since the body has a limited capacity to produce bicarbonate, Amorphical provides it in an enhanced form, ensuring it reaches inflamed areas and is absorbed at the highest possible rate. These facts are critical for patients, as they offer a new pathway for managing osteoporosis effectively.

Enhanced Absorption and Balanced Acidity with Nano-Amorphous Minerals

Amorphical has developed a product containing nano-amorphous minerals that provide more than just calcium, revolutionizing the approach to managing osteoporosis. Traditional attempts to treat the condition focused on symptoms without addressing the underlying cause. Understanding that osteoporosis is an inflammatory process changes everything. Inflammation triggers the immune system, leading to the release of cytokines, proteins that play a role in the body’s defense mechanisms. Inflammation also creates an acidic environment, further exacerbating the condition.

The main factor contributing to the inflammatory process is the body’s inability to produce enough bicarbonate to alter the local pH in bones. This acidic environment causes bone breakdown by disrupting the balance between osteoblasts (bone-building cells), which are suppressed by inflammation, and osteoclasts (bone-resorbing cells). This imbalance leads to the overactivity of cathepsin K, an enzyme that breaks down collagen, the substance that makes up 90% of the organic material in bone. As long as the cellular environment remains acidic, inflammation persists.

While the body naturally balances acidity through bicarbonate production, in chronic inflammation, increased production is required, but the body’s capacity is limited. Amorphical’s product, containing nano-amorphous minerals, produces bicarbonate upon absorption, representing a breakthrough that changes the approach to osteoporosis management.

A Solution with Revolutionary Impact

All efforts to manage osteoporosis must consider these new insights and act accordingly. We must address not only the calcium deficiency leading to bone loss but also the aging process itself, which is a chronic inflammatory breakdown of bone. Aging is a natural process, and while it’s impossible to prevent all age-related conditions, it is possible to slow the process and help the body manage it more effectively.

For U.S. customers, IGC is proud to offer Amorphical’s products, including the innovative solution for osteoporosis, Density. With a focus on reducing inflammation and enhancing calcium absorption, Density is now available through IGC, providing a unique opportunity for those seeking effective management of their osteoporosis.

Interested in learning more? Click here to discover how Density can help you >>